Epilesional Scarification: Preliminary Report of a New Approach to Local Immunotherapy With BCG

Stephen P. Richman, Giora M. Mavligit, Richard Wolk, Jordan U. Gutterman, Evan M. Hersh

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Because of the serious toxicity of intralesionally injected BCG, including high fever, local ulceration, chronic drainage, and disseminated BCG disease, 13 patients received local BCG immunotherapy by the new approach of epilesional scarification. Three patients had complete responses, four had partial responses, and six had no response. Toxic reactions were minimal compared to those reported for intralesionally given BCG.

Original languageEnglish (US)
Pages (from-to)1233-1235
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Volume234
Issue number12
DOIs
StatePublished - Dec 22 1975
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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