Epigenomic Actions of Environmental Arsenicals

Paul L. Severson, Bernard W. Futscher

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationToxicology and Epigenetics
PublisherJohn Wiley and Sons
Number of pages20
ISBN (Print)9781119976097
StatePublished - Aug 8 2012


  • Arsenic, 'Poison of Kings and King of Poisons'
  • Cellular ROS increase, following arsenic exposure
  • Environmental arsenic and plethora of human toxicities
  • Epigenomic actions of environmental arsenicals
  • Human cell lines, determining arsenical induced toxicity
  • Long-term arsenic exposure, cancer, in human mortality
  • Multiple mechanisms of arsenical toxicity, additive/synergistic
  • SAM methyl-donor for DNA methylation/arsenic methylation

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology

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