Epidemiology of urban tuberculosis in the United States, 2000-2007

Eyal Oren, Carla A. Winston, Robert Pratt, Valerie A. Robison, Masahiro Narita

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Objectives: We investigated tuberculosis (TB) incidence rates and characteristics of patients with TB in large US cities. Methods: Using the Centers for Disease Control and Prevention's National Tuberculosis Surveillance System data, we categorized 48 cities annually from 2000 to 2007 as reporting decreasing or nondecreasing rates with Joinpoint analysis. We compared demographic, clinical, and treatment characteristics of patients with TB using bivariate and multivariate analyses. Results: We found that 42448 patients with TB in 48 cities accounted for 36% of all US patients with TB; these cities comprised 15% of the US population. The average TB incidence rate in the 48 cities (12.1 per 100000) was higher than that in the US excluding the cities (3.8 per 100000) but decreased at a faster rate. Nineteen cities had decreasing rates; 29 cities had nondecreasing rates. Patient characteristics did not conclusively distinguish decreasing and nondecreasing rate cities. Conclusions: A significant TB burden occurs in large US cities. More than half (60%) of the selected cities did not show decreasing TB incidence rates. Studies of city-level variations in migration, socioeconomic status, and resources are needed to improve urban TB control.

Original languageEnglish (US)
Pages (from-to)1256-1263
Number of pages8
JournalAmerican journal of public health
Issue number7
StatePublished - Jul 1 2011

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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