Engineering light-emitting diode surgical light for near-infrared fluorescence image-guided surgical systems

Nan Zhu; Suman Mondal; Shengkui Gao; Samuel Achilefu; Viktor Gruev; Rongguang Liang

doi:10.1117/1.JBO.19.7.076018

Engineering light-emitting diode surgical light for near-infrared fluorescence image-guided surgical systems

Nan Zhu
, Suman Mondal
, Shengkui Gao
, Samuel Achilefu
, Viktor Gruev
, Rongguang Liang

Optical Sciences

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The near-infrared (NIR) fluorescence signal in the 700 to 900 nm from molecular probes used in fluorescence image-guided surgery (FIGS) is usually weak compared to the NIR component from white light-emitting diode surgical light, which is typically switched off during FIGS to enhance the molecular fluorescence contrast of the image. We propose a simple solution to this critical issue in FIGS by removing NIR light from surgical light with a low cost commercial 3M cool mirror film 330.

Original language	English (US)
Article number	076018
Journal	Journal of biomedical optics
Volume	19
Issue number	7
DOIs	https://doi.org/10.1117/1.JBO.19.7.076018
State	Published - Jul 2014

Keywords

fluorescence imaging
image-guided surgery
imaging system

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Biomedical Engineering

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10.1117/1.JBO.19.7.076018

Cite this

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title = "Engineering light-emitting diode surgical light for near-infrared fluorescence image-guided surgical systems",

abstract = "The near-infrared (NIR) fluorescence signal in the 700 to 900 nm from molecular probes used in fluorescence image-guided surgery (FIGS) is usually weak compared to the NIR component from white light-emitting diode surgical light, which is typically switched off during FIGS to enhance the molecular fluorescence contrast of the image. We propose a simple solution to this critical issue in FIGS by removing NIR light from surgical light with a low cost commercial 3M cool mirror film 330.",

keywords = "fluorescence imaging, image-guided surgery, imaging system",

author = "Nan Zhu and Suman Mondal and Shengkui Gao and Samuel Achilefu and Viktor Gruev and Rongguang Liang",

note = "Funding Information: Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Number R01CA171651. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We thank Dr. Farid Gharagozloo, Keith Mass, and Duran Powers at University of Arizona Medical Center for their help on the experiment in the surgical room. We also thank 3M for providing 3M cool mirror film 330.",

year = "2014",

month = jul,

doi = "10.1117/1.JBO.19.7.076018",

language = "English (US)",

volume = "19",

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T1 - Engineering light-emitting diode surgical light for near-infrared fluorescence image-guided surgical systems

AU - Zhu, Nan

AU - Mondal, Suman

AU - Gao, Shengkui

AU - Achilefu, Samuel

AU - Gruev, Viktor

AU - Liang, Rongguang

N1 - Funding Information: Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Number R01CA171651. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We thank Dr. Farid Gharagozloo, Keith Mass, and Duran Powers at University of Arizona Medical Center for their help on the experiment in the surgical room. We also thank 3M for providing 3M cool mirror film 330.

PY - 2014/7

Y1 - 2014/7

N2 - The near-infrared (NIR) fluorescence signal in the 700 to 900 nm from molecular probes used in fluorescence image-guided surgery (FIGS) is usually weak compared to the NIR component from white light-emitting diode surgical light, which is typically switched off during FIGS to enhance the molecular fluorescence contrast of the image. We propose a simple solution to this critical issue in FIGS by removing NIR light from surgical light with a low cost commercial 3M cool mirror film 330.

AB - The near-infrared (NIR) fluorescence signal in the 700 to 900 nm from molecular probes used in fluorescence image-guided surgery (FIGS) is usually weak compared to the NIR component from white light-emitting diode surgical light, which is typically switched off during FIGS to enhance the molecular fluorescence contrast of the image. We propose a simple solution to this critical issue in FIGS by removing NIR light from surgical light with a low cost commercial 3M cool mirror film 330.

KW - fluorescence imaging

KW - image-guided surgery

KW - imaging system

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Engineering light-emitting diode surgical light for near-infrared fluorescence image-guided surgical systems

Abstract

Keywords

ASJC Scopus subject areas

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