Abstract
An unprecedented organocatalytic enantioselective [4 + 2] cycloaddition reaction of vinyl quinolines with dienals is achieved with the synergistic activation of CH3SO3H and a chiral aminocatalyst. The power of the process is demonstrated by its high efficiency of the production of new synthetically and biologically valued chiral quinoline architectures in high yields and with excellent enantioselectivities.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6061-6066 |
| Number of pages | 6 |
| Journal | Organic Letters |
| Volume | 22 |
| Issue number | 15 |
| DOIs | |
| State | Published - Aug 7 2020 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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CCDC 1982431: Experimental Crystal Structure Determination
Chen, J. (Contributor), Fu, Y. (Contributor), Yu, Y. (Contributor), Wang, J.-R. (Contributor), Guo, Y.-W. (Contributor), Li, H. (Contributor) & Wang, W. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc24jwdz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24jwdz&sid=DataCite
Dataset
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CCDC 1982440: Experimental Crystal Structure Determination
Chen, J. (Contributor), Fu, Y. (Contributor), Yu, Y. (Contributor), Wang, J.-R. (Contributor), Guo, Y.-W. (Contributor), Li, H. (Contributor) & Wang, W. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc24jwp8, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24jwp8&sid=DataCite
Dataset