Elution of in vivo bound antiprostatic epithelial antibodies following multiple cryotherapy of carcinoma of prostate

Antibodies reactive with the cytoplasmic membrane or intercellular areas of autologous human and monkey prostatic secretory epithelial cells have been demonstrated by immunofluorescence in an eluate prepared from prostatic tissue obtained from a patient with metastatic adenocarcinoma of the prostate following multiple cryotherapy of his primary prostatic tumor. Elution of antiprostatic antibodies provides preliminary evidence that prostatic tissue (tumor?)-specific or tumor-associated antigens are liberated into the circulation following cryotherapy of the prostate in man.