Abstract
We evaluated the minimal molecular and cellular requirements for elicitation of anti-vesicular stomatitis virus (VSV) cytotoxic T lymphocytes (CTL). The results indicated that lipid vesicles containing the purified major surface glycoprotein of VSV (G protein) and purified H-2K(k) glycoproteins elicited specific H-2K(k)-restricted anti-VSV CTL. These antiviral CTL were shown to be Ly 1-, 2+. However, both Ly 1+, 2- and Ly1-, 2+ T-cell subpopulations were shown to be required for elicitation of these CTL.
Original language | English (US) |
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Pages (from-to) | 513-517 |
Number of pages | 5 |
Journal | Infection and Immunity |
Volume | 32 |
Issue number | 2 |
DOIs | |
State | Published - 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases