Electro-oculography in Best's macular dystrophy

Harold E. Cross; Leslie Bard

doi:10.1016/0002-9394(74)90603-5

Electro-oculography in Best's macular dystrophy

Harold E. Cross, Leslie Bard

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

Electro-oculograms (EOG) obtained from 105 members of eight pedigrees of Best's macular dystrophy revealed that individuals with funduscopic abnormalities consistent with this diagnosis in every case had EOG light/dark ratios below 1.55, whereas those who were offspring of normal parents had ratios greater than 1.85. Among ophthalmoscopically normal offspring of affected parents, distribution of the EOG ratio was bimodal. Only three individuals in the latter group had values in the gray zone between 1.65 and 1.85. The EOG was a useful and reliable test for the diagnosis and genetic counseling of families with Best's macular disease.

Original language	English (US)
Pages (from-to)	46-50
Number of pages	5
Journal	American Journal of Ophthalmology
Volume	77
Issue number	1
DOIs	https://doi.org/10.1016/0002-9394(74)90603-5
State	Published - Jan 1974
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1016/0002-9394(74)90603-5

Cite this

@article{b73d5d4e85724153953299f610a31b70,

title = "Electro-oculography in Best's macular dystrophy",

abstract = "Electro-oculograms (EOG) obtained from 105 members of eight pedigrees of Best's macular dystrophy revealed that individuals with funduscopic abnormalities consistent with this diagnosis in every case had EOG light/dark ratios below 1.55, whereas those who were offspring of normal parents had ratios greater than 1.85. Among ophthalmoscopically normal offspring of affected parents, distribution of the EOG ratio was bimodal. Only three individuals in the latter group had values in the gray zone between 1.65 and 1.85. The EOG was a useful and reliable test for the diagnosis and genetic counseling of families with Best's macular disease.",

author = "Cross, {Harold E.} and Leslie Bard",

year = "1974",

month = jan,

doi = "10.1016/0002-9394(74)90603-5",

language = "English (US)",

volume = "77",

pages = "46--50",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Electro-oculography in Best's macular dystrophy

AU - Cross, Harold E.

AU - Bard, Leslie

PY - 1974/1

Y1 - 1974/1

N2 - Electro-oculograms (EOG) obtained from 105 members of eight pedigrees of Best's macular dystrophy revealed that individuals with funduscopic abnormalities consistent with this diagnosis in every case had EOG light/dark ratios below 1.55, whereas those who were offspring of normal parents had ratios greater than 1.85. Among ophthalmoscopically normal offspring of affected parents, distribution of the EOG ratio was bimodal. Only three individuals in the latter group had values in the gray zone between 1.65 and 1.85. The EOG was a useful and reliable test for the diagnosis and genetic counseling of families with Best's macular disease.

AB - Electro-oculograms (EOG) obtained from 105 members of eight pedigrees of Best's macular dystrophy revealed that individuals with funduscopic abnormalities consistent with this diagnosis in every case had EOG light/dark ratios below 1.55, whereas those who were offspring of normal parents had ratios greater than 1.85. Among ophthalmoscopically normal offspring of affected parents, distribution of the EOG ratio was bimodal. Only three individuals in the latter group had values in the gray zone between 1.65 and 1.85. The EOG was a useful and reliable test for the diagnosis and genetic counseling of families with Best's macular disease.

UR - http://www.scopus.com/inward/record.url?scp=0015962403&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015962403&partnerID=8YFLogxK

U2 - 10.1016/0002-9394(74)90603-5

DO - 10.1016/0002-9394(74)90603-5

M3 - Article

C2 - 4824173

AN - SCOPUS:0015962403

SN - 0002-9394

VL - 77

SP - 46

EP - 50

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 1

ER -

Electro-oculography in Best's macular dystrophy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this