Abstract
To determine whether arachidonic acid (AA) alters alveolar epithelial permeability, we studied the effect of both continuous intravenous and aerosolized AA on clearance of [99m]Tc-DTPA from lung to blood in rabbits. Although intravenous AA increased prostacylin production and aerosolized AA decreased systemic blood pressure, neither continuous intravenous nor aerosolized AA augmented alveolar epithelial permeability.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 113-116 |
| Number of pages | 4 |
| Journal | Research Communications in Chemical Pathology and Pharmacology |
| Volume | 72 |
| Issue number | 1 |
| State | Published - 1991 |
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- Pathology and Forensic Medicine
- Toxicology
- Pharmacology