Effects of hormone replacement therapy on QT interval

Jennifer A. Larsen, Roderick H. Tung, Ramana Sadananda, Jeffrey J. Goldberger, George Horvath, Michele A. Parker, Alan H. Kadish

Research output: Contribution to journalArticlepeer-review

69 Scopus citations


We evaluated the electrocardiograms of 208 postmenopausal women (ages 40 to ≥70 years) without heart disease, medications that could alter the QT interval, use of vaginal estrogens, unknown hormone replacement therapy, or electrocardiographic abnormalities both with (n = 76) and without (n = 132) hormone replacement therapy, and found no significant effects of hormone replacement therapy status on heart rate, QT interval, or the corrected QT interval. Thus, estrogen and/or progesterone effect does not explain the gender differences in myocardial repolarization.

Original languageEnglish (US)
Pages (from-to)993-995
Number of pages3
JournalAmerican Journal of Cardiology
Issue number8
StatePublished - Oct 15 1998
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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