TY - JOUR
T1 - Effects of hormone replacement therapy on QT interval
AU - Larsen, Jennifer A.
AU - Tung, Roderick H.
AU - Sadananda, Ramana
AU - Goldberger, Jeffrey J.
AU - Horvath, George
AU - Parker, Michele A.
AU - Kadish, Alan H.
N1 - Funding Information:
This study was supported by Grant #RFA PA 96-023 from the National Institute of Aging, Baltimore, Maryland.
PY - 1998/10/15
Y1 - 1998/10/15
N2 - We evaluated the electrocardiograms of 208 postmenopausal women (ages 40 to ≥70 years) without heart disease, medications that could alter the QT interval, use of vaginal estrogens, unknown hormone replacement therapy, or electrocardiographic abnormalities both with (n = 76) and without (n = 132) hormone replacement therapy, and found no significant effects of hormone replacement therapy status on heart rate, QT interval, or the corrected QT interval. Thus, estrogen and/or progesterone effect does not explain the gender differences in myocardial repolarization.
AB - We evaluated the electrocardiograms of 208 postmenopausal women (ages 40 to ≥70 years) without heart disease, medications that could alter the QT interval, use of vaginal estrogens, unknown hormone replacement therapy, or electrocardiographic abnormalities both with (n = 76) and without (n = 132) hormone replacement therapy, and found no significant effects of hormone replacement therapy status on heart rate, QT interval, or the corrected QT interval. Thus, estrogen and/or progesterone effect does not explain the gender differences in myocardial repolarization.
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U2 - 10.1016/S0002-9149(98)00523-2
DO - 10.1016/S0002-9149(98)00523-2
M3 - Article
C2 - 9794362
AN - SCOPUS:0032532342
SN - 0002-9149
VL - 82
SP - 993
EP - 995
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 8
ER -