We studied the effects of halothane anesthesia (n = 6) and fentanyl anesthesia (n = 9; 50-100 μg/kg) on plasma β-endorphin immunoreactivity as a measure of stress response during coronary artery bypass grafting, including cardiopulmonary bypass. Plasma levels of β-endorphin immunoreactivity measured prior to induction, after induction, after intubation, after skin incision, during cardiopulmonary bypass, and on leaving the operating room were significantly higher in patients given halothane during cardiopulmonary bypass and on leaving the operating room than they were in patients given fentanyl.
|Original language||English (US)|
|Number of pages||4|
|Journal||Anesthesia and analgesia|
|State||Published - 1985|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine