TY - CHAP
T1 - Effects of antioxidants on tobacco smoke - associated cardiovascular damage
AU - Watson, Ronald R.
AU - Rodriquez, Julian
AU - Chen, Yinhong
N1 - Funding Information:
In this paper we have presented a systematic approach based on regions for automated design of multi-piece Rapid Tooling molds. Face connectivity and demoldability of mold pieces are two main concerns in multi-pieces mold design. They all should be considered in a problem formulation. For a given part, the convex and concave properties of its faces are the main factors to decide demoldability of mold pieces, and therefore its mold design. Correspondingly concave regions and convex faces are suitable basic elements for mold design. Although complete splitting can generate a unique result of concave regions and convex faces for a part, the running time of the approach is not feasible. So some heuristics are needed to select splitting surface and splitting criterion in region splitting. As is true for any heuristic search technique, an optimum solution cannot be guaranteed. However, the technique does give a feasible solution. The results shown in Section 6 validate the efficacy and robustness of our approaches. ACKNOWLEDGEMENTS We gratefully acknowledge the support from NSF grant DMI-9618039 and from the member companies of the Rapid Prototyping and Manufacturing Institute at Georgia Tech. Also, we acknowledge the usage of Systems Realization Laboratory facilities.
Publisher Copyright:
© 2001 by Taylor & Francis Group, LLC.
PY - 2000/1/1
Y1 - 2000/1/1
N2 - Tobacco smoke exposure contributes significantly to cardiovascular damage through a number of pathways, including direct toxicity to the endothelium by free radicals, indirect effect of platelet aggregation, as well as increased catecholamine, homocysteine, and chronic oxidative changes occurring in LDL cholesterol. All ultimately disrupt myocardial structure and function for increased coronary heart disease.
AB - Tobacco smoke exposure contributes significantly to cardiovascular damage through a number of pathways, including direct toxicity to the endothelium by free radicals, indirect effect of platelet aggregation, as well as increased catecholamine, homocysteine, and chronic oxidative changes occurring in LDL cholesterol. All ultimately disrupt myocardial structure and function for increased coronary heart disease.
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M3 - Chapter
AN - SCOPUS:85057355486
SN - 9780849303111
SP - 59
EP - 68
BT - Environmental Tobacco Smoke
PB - CRC Press
ER -