Specific anti Ia serum in combination with rabbit complement removed the B lymphocyte population normally responsive to LPS mitogenic stimulation. Significant inhibition of this proliferative response was also obtained by brief periods of cell pretreatment with anti Ia antibodies, but not with specific anti H 2K antibodies. The population of splenic B cells resistant to anti Thy 1.2 serum and complement was blocked in a very similar manner by anti Ia serum, but not by anti H 2 serum.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of Immunology|
|State||Published - 1975|
ASJC Scopus subject areas
- Immunology and Allergy