Effects of age, sex and diagnostic x-rays on chromosome damage

Amos Norman; Sachiko Cochran; Doris Bass; Denise Roe

doi:10.1080/09553008414551451

Effects of age, sex and diagnostic x-rays on chromosome damage

Amos Norman, Sachiko Cochran, Doris Bass, Denise Roe

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The frequency of micronuclei assayed in lymphocytes obtained from 73 young adults increases significantly with the age, but not the sex, of the donor. The dose of medical X-rays absorbed by the lymphocytes in the 2 years before the examination has no significant effect on micronucleus frequency, provided the data are adjusted for age. However, a small significant increase in frequency is associated with X-ray examinations that involve the injection of contrast media into the blood.

Original language	English (US)
Pages (from-to)	317-321
Number of pages	5
Journal	International Journal of Radiation Biology
Volume	46
Issue number	3
DOIs	https://doi.org/10.1080/09553008414551451
State	Published - 1984
Externally published	Yes

Keywords

Age
Chromosome damage
Lymphocytes
Sex

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

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10.1080/09553008414551451

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title = "Effects of age, sex and diagnostic x-rays on chromosome damage",

abstract = "The frequency of micronuclei assayed in lymphocytes obtained from 73 young adults increases significantly with the age, but not the sex, of the donor. The dose of medical X-rays absorbed by the lymphocytes in the 2 years before the examination has no significant effect on micronucleus frequency, provided the data are adjusted for age. However, a small significant increase in frequency is associated with X-ray examinations that involve the injection of contrast media into the blood.",

keywords = "Age, Chromosome damage, Lymphocytes, Sex",

author = "Amos Norman and Sachiko Cochran and Doris Bass and Denise Roe",

note = "Funding Information: This work was supported in part by contract DE-AT03-82ER60038 between the U.S. Department of Energy and the University of California.",

year = "1984",

doi = "10.1080/09553008414551451",

language = "English (US)",

volume = "46",

pages = "317--321",

journal = "International Journal of Radiation Biology",

issn = "0955-3002",

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TY - JOUR

T1 - Effects of age, sex and diagnostic x-rays on chromosome damage

AU - Norman, Amos

AU - Cochran, Sachiko

AU - Bass, Doris

AU - Roe, Denise

N1 - Funding Information: This work was supported in part by contract DE-AT03-82ER60038 between the U.S. Department of Energy and the University of California.

PY - 1984

Y1 - 1984

N2 - The frequency of micronuclei assayed in lymphocytes obtained from 73 young adults increases significantly with the age, but not the sex, of the donor. The dose of medical X-rays absorbed by the lymphocytes in the 2 years before the examination has no significant effect on micronucleus frequency, provided the data are adjusted for age. However, a small significant increase in frequency is associated with X-ray examinations that involve the injection of contrast media into the blood.

AB - The frequency of micronuclei assayed in lymphocytes obtained from 73 young adults increases significantly with the age, but not the sex, of the donor. The dose of medical X-rays absorbed by the lymphocytes in the 2 years before the examination has no significant effect on micronucleus frequency, provided the data are adjusted for age. However, a small significant increase in frequency is associated with X-ray examinations that involve the injection of contrast media into the blood.

KW - Age

KW - Chromosome damage

KW - Lymphocytes

KW - Sex

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DO - 10.1080/09553008414551451

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AN - SCOPUS:0021207732

SN - 0955-3002

VL - 46

SP - 317

EP - 321

JO - International Journal of Radiation Biology

JF - International Journal of Radiation Biology

IS - 3

ER -

Effects of age, sex and diagnostic x-rays on chromosome damage

Abstract

Keywords

ASJC Scopus subject areas

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