The literature dealing with estrogenic effect on the immunologic responsiveness to tumor in patients is reviewed briefly. It is thought that estrogen may have a dual suppressive effect: 1) on the synthesis of autoantigen; and 2) on the immunologic responsiveness of the host to tumor. This is particularly true for hormonally responsive tumors, e.g., of the breast and the prostate. Hormonal therapy in these types of tumors is still open to question.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Dec 1978|
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