Abstract
Nonlactating, nonpregnant Holstein cows were used to examine the effects of an im injection of reserpine. A 5-mg reserpine injection resulted in a rapid (within 0.5 hr) and sustained (at least 24 hr) elevation of serum prolactin. Peak prolactin levels (283 ng/ml) occurred 3 hr postinjection. Serum glucocorticoid and growth hormone concentrations were unaffected by reserpine injection. Two sequential injections of 5 mg of reserpine given at 48-hr intervals gave nearly identical prolactin responses. The prolactin response to reserpine was dose dependent with 1 mg giving approximately 39.5% of the response obtained with 5 mg of reserpine.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 189-192 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 155 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1977 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)