Effect of quinidine on the heart rate and blood pressure response to treadmill exercise

Paul E. Fenster; Christine Dahl; Frank I. Marcus; Gordon A. Ewy

doi:10.1016/0002-8703(82)90152-1

Effect of quinidine on the heart rate and blood pressure response to treadmill exercise

Paul E. Fenster, Christine Dahl, Frank I. Marcus, Gordon A. Ewy

Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The effect of quinidine on the heart rate and blood pressure response to treadmill exercise was evaluated in 17 normal subjects. Quinidine significantly increased the heart rate at rest and at low levels of exercise. Quinidine had no significant effect on the systolic blood pressure response to any work load. However, quinidine significantly decreased the systolic blood pressure at all exercising heart rates, compared to control, in 15 of the 17 subjects. The magnitude of the decrease in systolic pressure ranged from 1 to 22 mm Hg, with a mean of 10 mm Hg.

Original language	English (US)
Pages (from-to)	1244-1247
Number of pages	4
Journal	American Heart Journal
Volume	104
Issue number	6
DOIs	https://doi.org/10.1016/0002-8703(82)90152-1
State	Published - Dec 1982

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/0002-8703(82)90152-1

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title = "Effect of quinidine on the heart rate and blood pressure response to treadmill exercise",

abstract = "The effect of quinidine on the heart rate and blood pressure response to treadmill exercise was evaluated in 17 normal subjects. Quinidine significantly increased the heart rate at rest and at low levels of exercise. Quinidine had no significant effect on the systolic blood pressure response to any work load. However, quinidine significantly decreased the systolic blood pressure at all exercising heart rates, compared to control, in 15 of the 17 subjects. The magnitude of the decrease in systolic pressure ranged from 1 to 22 mm Hg, with a mean of 10 mm Hg.",

author = "Fenster, {Paul E.} and Christine Dahl and Marcus, {Frank I.} and Ewy, {Gordon A.}",

note = "Funding Information: From the Department Health Sciences Center. This work was done during the tenure Scientist of the American Heart Association. for publication June 2, 1981. requests: Paul E. Fenster, M.D., Sciences Center, Tucson, AZ 85724.",

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AU - Ewy, Gordon A.

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N2 - The effect of quinidine on the heart rate and blood pressure response to treadmill exercise was evaluated in 17 normal subjects. Quinidine significantly increased the heart rate at rest and at low levels of exercise. Quinidine had no significant effect on the systolic blood pressure response to any work load. However, quinidine significantly decreased the systolic blood pressure at all exercising heart rates, compared to control, in 15 of the 17 subjects. The magnitude of the decrease in systolic pressure ranged from 1 to 22 mm Hg, with a mean of 10 mm Hg.

AB - The effect of quinidine on the heart rate and blood pressure response to treadmill exercise was evaluated in 17 normal subjects. Quinidine significantly increased the heart rate at rest and at low levels of exercise. Quinidine had no significant effect on the systolic blood pressure response to any work load. However, quinidine significantly decreased the systolic blood pressure at all exercising heart rates, compared to control, in 15 of the 17 subjects. The magnitude of the decrease in systolic pressure ranged from 1 to 22 mm Hg, with a mean of 10 mm Hg.

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Effect of quinidine on the heart rate and blood pressure response to treadmill exercise

Abstract

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