Early-life risk factors for reversible and irreversible airflow limitation in young adults: Findings from the BAMSE birth cohort

Gang Wang; Inger Kull; Anna Bergström; Jenny Hallberg; Petra Um Bergström; Stefano Guerra; Goran Pershagen; Olena Gruzieva; Marianne Van Hage; Antonios Georgelis; Christer Janson; Anders Lindén; Erik Melén

doi:10.1136/thoraxjnl-2020-215884

Early-life risk factors for reversible and irreversible airflow limitation in young adults: Findings from the BAMSE birth cohort

Gang Wang, Inger Kull, Anna Bergström, Jenny Hallberg, Petra Um Bergström, Stefano Guerra, Goran Pershagen, Olena Gruzieva, Marianne Van Hage, Antonios Georgelis, Christer Janson, Anders Lindén, Erik Melén

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27 Scopus citations

Abstract

We aimed to determine prevalence and early-life risk factors for reversible and irreversible airflow limitation in young adults from the general population. Among young adults in their 20s, the prevalence was 5.3% for reversible airflow limitation and 2.0% for irreversible airflow limitation. While parental asthma was the only risk factor for development of reversible airflow limitation, the risk factors for development of irreversible airflow limitation were current asthma, childhood respiratory tract infections and asthma, and exposure to air pollution.

Original language	English (US)
Pages (from-to)	503-507
Number of pages	5
Journal	Thorax
Volume	76
Issue number	5
DOIs	https://doi.org/10.1136/thoraxjnl-2020-215884
State	Published - May 1 2021

Keywords

COPD epidemiology

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1136/thoraxjnl-2020-215884

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Wang, G., Kull, I., Bergström, A., Hallberg, J., Bergström, P. U., Guerra, S., Pershagen, G., Gruzieva, O., Van Hage, M., Georgelis, A., Janson, C., Lindén, A., & Melén, E. (2021). Early-life risk factors for reversible and irreversible airflow limitation in young adults: Findings from the BAMSE birth cohort. Thorax, 76(5), 503-507. https://doi.org/10.1136/thoraxjnl-2020-215884

Wang, G, Kull, I, Bergström, A, Hallberg, J, Bergström, PU, Guerra, S, Pershagen, G, Gruzieva, O, Van Hage, M, Georgelis, A, Janson, C, Lindén, A & Melén, E 2021, 'Early-life risk factors for reversible and irreversible airflow limitation in young adults: Findings from the BAMSE birth cohort', Thorax, vol. 76, no. 5, pp. 503-507. https://doi.org/10.1136/thoraxjnl-2020-215884

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AU - Wang, Gang

AU - Kull, Inger

AU - Bergström, Anna

AU - Hallberg, Jenny

AU - Bergström, Petra Um

AU - Guerra, Stefano

AU - Pershagen, Goran

AU - Gruzieva, Olena

AU - Van Hage, Marianne

AU - Georgelis, Antonios

AU - Janson, Christer

AU - Lindén, Anders

AU - Melén, Erik

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AB - We aimed to determine prevalence and early-life risk factors for reversible and irreversible airflow limitation in young adults from the general population. Among young adults in their 20s, the prevalence was 5.3% for reversible airflow limitation and 2.0% for irreversible airflow limitation. While parental asthma was the only risk factor for development of reversible airflow limitation, the risk factors for development of irreversible airflow limitation were current asthma, childhood respiratory tract infections and asthma, and exposure to air pollution.

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Early-life risk factors for reversible and irreversible airflow limitation in young adults: Findings from the BAMSE birth cohort

Abstract

Keywords

ASJC Scopus subject areas

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