TY - GEN
T1 - Dynamic behaviour of a dacron aortic graft
AU - Tubaldi, Eleonora
AU - Ferrari, Giovanni
AU - Balasubramanian, Prabakaran
AU - Amabili, Marco
N1 - Funding Information:
The authors acknowledge the financial support of the NSERC Discovery Grant, the Canada Foundation for Innovation and the Canada Research Chair programs. We greatly tank Prof. Rosaire Mongrain of McGill University who has kindly provided the Harvard Apparatus pump used in the experiments.
Publisher Copyright:
Copyright © 2019 ASME.
PY - 2019
Y1 - 2019
N2 - Woven Dacron grafts are still considered the clinical standard practice in thoracic vascular reconstruction in the case of aortic aneurysm and acute dissection. Despite its characteristics of biocompatibility and durability, very little is known about the dynamic response of Dacron grafts and about their side effects on the heart workload and cardiovascular system. In this study, physiological blood flow conditions are imposed in a Dacron graft via a specifically-developed mock circulatory loop. The effects of different physiological pulsation-per-minute rates are investigated. Since the Dacron prosthesis is extremely stiffer circumferentially and compliant axially with respect to an aortic segment of the same length, bending oscillations are preferred by the graft. This leads to a very significant different dynamic behavior with respect to the replaced human aortic portion altering cardiovascular pressure and blood flow dynamics and eventually causing long-term implant complications.
AB - Woven Dacron grafts are still considered the clinical standard practice in thoracic vascular reconstruction in the case of aortic aneurysm and acute dissection. Despite its characteristics of biocompatibility and durability, very little is known about the dynamic response of Dacron grafts and about their side effects on the heart workload and cardiovascular system. In this study, physiological blood flow conditions are imposed in a Dacron graft via a specifically-developed mock circulatory loop. The effects of different physiological pulsation-per-minute rates are investigated. Since the Dacron prosthesis is extremely stiffer circumferentially and compliant axially with respect to an aortic segment of the same length, bending oscillations are preferred by the graft. This leads to a very significant different dynamic behavior with respect to the replaced human aortic portion altering cardiovascular pressure and blood flow dynamics and eventually causing long-term implant complications.
KW - Dynamics
KW - Mock circulatory loop
KW - Woven Dacron prosthesis
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U2 - 10.1115/IMECE2019-11520
DO - 10.1115/IMECE2019-11520
M3 - Conference contribution
AN - SCOPUS:85078868372
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
BT - Biomedical and Biotechnology Engineering
PB - American Society of Mechanical Engineers (ASME)
T2 - ASME 2019 International Mechanical Engineering Congress and Exposition, IMECE 2019
Y2 - 11 November 2019 through 14 November 2019
ER -