Does DHEA supplementation affect muscle mass?

R. R. Watson, S. Jiang

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations


DHEA (dehydroepiandrosterone) production declines dramatically with increasing age in people as they loose muscle mass. Animal studies have not shown that DHEA replacement affects body or muscle weight in animals, but does reduce lipids and reduces oxidation, increased with ageing. One research group has shown that growth hormones increase while others decrease during DHEA supplementation of older people. However, DHEA's effect on muscle mass in humans is unclear. DHEA supplementation does restore DHEA levels without apparent toxicity.

Original languageEnglish (US)
Pages (from-to)1725-1728
Number of pages4
JournalExpert Opinion on Investigational Drugs
Issue number12
StatePublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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