Divergent Synthesis of Imidazoles and Quinazolines via Pd(OAc)2-Catalyzed Annulation of N-Allylamidines

Li Xu, Hongxian Li, Ziyang Liao, Kaiyan Lou, Hexin Xie, Hao Li, Wei Wang

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

A Pd(OAc)2-catalyzed divergent synthesis of multisubstituted imidazoles and quinazolines from N-allylamidines has been developed. In the presence of oxidant O2 from air and/or a ligand and Pd(OAc)2, imidazoles were obtained. Nonetheless, under microwave (MW) irradiation in a sealed system, quinazolines as major products were produced.

Original languageEnglish (US)
Pages (from-to)3434-3437
Number of pages4
JournalOrganic Letters
Volume17
Issue number14
DOIs
StatePublished - Jul 17 2015
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Divergent Synthesis of Imidazoles and Quinazolines via Pd(OAc)2-Catalyzed Annulation of N-Allylamidines'. Together they form a unique fingerprint.

Cite this