Discovery of imidazo[1,2-a]pyridine-thiophene derivatives as FLT3 and FLT3 mutants inhibitors for acute myeloid leukemia through structure-based optimization of an NEK2 inhibitor

Lingtian Zhang, Naga Rajiv Lakkaniga, Jaideep B. Bharate, Nicholas Mcconnell, Xiuqi Wang, Anupreet Kharbanda, Yuet Kin Leung, Brendan Frett, Neil P. Shah, Hong yu Li

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