Direct, organocatalytic α-sulfenylation of aldehydes and ketones

Wei Wang, Hao Li, Jian Wang, Lixin Liao

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


A method for direct sulfenylation of aldehydes and ketones, catalyzed by a novel pyrrolidine trifluoromethanesulfonamide organocatalyst, has been developed. This process serves as an efficient and mild approach to the preparation of α-phenylthio-ketones and -aldehydes.

Original languageEnglish (US)
Pages (from-to)8229-8231
Number of pages3
JournalTetrahedron Letters
Issue number44
StatePublished - Oct 25 2004
Externally publishedYes


  • Aldehydes
  • Ketones
  • Organocatalyst
  • Pyrrolidine sulfonamide
  • α-Sulfenylation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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