Direct, highly enantioselective pyrrolidine sulfonamide catalyzed Michael addition of aldehydes to nitrostyrenes

Wei Wang, Jian Wang, Hao Li

Research output: Contribution to journalArticlepeer-review

373 Scopus citations

Abstract

Just can't get enough: The highly versatile pyrrolidine sulfonamide organocatalyst 1, which has been used in α-aminoxylation and Mannich-type reactions, also mediates diastereo- and enantioselective Michael addition reactions of aldehydes and ketones to nitroolefins (see scheme).

Original languageEnglish (US)
Pages (from-to)1369-1371
Number of pages3
JournalAngewandte Chemie - International Edition
Volume44
Issue number9
DOIs
StatePublished - Feb 18 2005
Externally publishedYes

Keywords

  • Aldehydes
  • Asymmetric catalysis
  • Michael addition
  • Nitroalkenes
  • Organocatalysts

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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