Direct deprotonation of aliphatic sulfides

Yunqi Liu; Richard S. Glass

doi:10.1016/S0040-4039(97)10313-6

Direct deprotonation of aliphatic sulfides

Yunqi Liu
, Richard S. Glass

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Alkylmethyl sulfides are regioselectively deprotonated by n-butyllithium and potassium tert-butoxide at the methyl group in good yields. Thiolane and thiane are deprotonated under the same conditions at the α-position in good yield.

Original language	English (US)
Pages (from-to)	8615-8618
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	50
DOIs	https://doi.org/10.1016/S0040-4039(97)10313-6
State	Published - Dec 15 1997
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)10313-6

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@article{e00a3bfe7fc444a3938e6d4373b91eb3,

title = "Direct deprotonation of aliphatic sulfides",

abstract = "Alkylmethyl sulfides are regioselectively deprotonated by n-butyllithium and potassium tert-butoxide at the methyl group in good yields. Thiolane and thiane are deprotonated under the same conditions at the α-position in good yield.",

author = "Yunqi Liu and Glass, \{Richard S.\}",

note = "Funding Information: Acknowledgment. The authors gratefully acknowledge support of this work by the National Science",

year = "1997",

month = dec,

day = "15",

doi = "10.1016/S0040-4039(97)10313-6",

language = "English (US)",

volume = "38",

pages = "8615--8618",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "50",

}

TY - JOUR

T1 - Direct deprotonation of aliphatic sulfides

AU - Liu, Yunqi

AU - Glass, Richard S.

N1 - Funding Information: Acknowledgment. The authors gratefully acknowledge support of this work by the National Science

PY - 1997/12/15

Y1 - 1997/12/15

N2 - Alkylmethyl sulfides are regioselectively deprotonated by n-butyllithium and potassium tert-butoxide at the methyl group in good yields. Thiolane and thiane are deprotonated under the same conditions at the α-position in good yield.

AB - Alkylmethyl sulfides are regioselectively deprotonated by n-butyllithium and potassium tert-butoxide at the methyl group in good yields. Thiolane and thiane are deprotonated under the same conditions at the α-position in good yield.

UR - https://www.scopus.com/pages/publications/0030822975

UR - https://www.scopus.com/pages/publications/0030822975#tab=citedBy

U2 - 10.1016/S0040-4039(97)10313-6

DO - 10.1016/S0040-4039(97)10313-6

M3 - Article

AN - SCOPUS:0030822975

SN - 0040-4039

VL - 38

SP - 8615

EP - 8618

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 50

ER -

Direct deprotonation of aliphatic sulfides

Abstract

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