Direct deprotonation of aliphatic sulfides

Yunqi Liu, Richard S. Glass

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Alkylmethyl sulfides are regioselectively deprotonated by n-butyllithium and potassium tert-butoxide at the methyl group in good yields. Thiolane and thiane are deprotonated under the same conditions at the α-position in good yield.

Original languageEnglish (US)
Pages (from-to)8615-8618
Number of pages4
JournalTetrahedron Letters
Issue number50
StatePublished - Dec 15 1997

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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