Digital breast tomosynthesis: State of the art1

Srinivasan Vedantham, Andrew Karellas, Gopal R. Vijayaraghavan, Daniel B. Kopans

Research output: Contribution to journalArticlepeer-review

169 Scopus citations


This topical review on digital breast tomosynthesis (DBT) is provided with the intent of describing the state of the art in terms of technology, results from recent clinical studies, advanced applications, and ongoing efforts to develop multimodality imaging systems that include DBT. Particular emphasis is placed on clinical studies. The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening. Retrospective multireader multicase studies show either noninferiority or superiority of DBT compared with mammography. Methods to curtail radiation dose are of importance.

Original languageEnglish (US)
Pages (from-to)663-684
Number of pages22
Issue number3
StatePublished - Dec 2015

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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