Development and numerical solution of a mechanistic model for corneal tissue ablation with the 193 nm argon fluoride excimer laser

Brian T. Fisher, David W. Hahn

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We detail the development and implementation of a global ablation model that incorporates a dynamically changing tissue absorption coefficient. Detailed spectroscopic measurements rule out plasma-shielding effects during the laser-tissue interaction and thereby support a photochemical mechanism. The model predicts ablation rate behavior that agrees well with a variety of experimental ablation rate data and that substantially deviates from a static Beer-Lambert model. The dynamic model predicts an enhancement in the tissue absorption coefficient of about 25%-50% as compared with the initial, static value. In addition, the model predicts an increase in the tissue ablation rate as corneal hydration increases, which may provide additional insight into variations in refractive surgery outcome.

Original languageEnglish (US)
Pages (from-to)265-277
Number of pages13
JournalJournal of the Optical Society of America A: Optics and Image Science, and Vision
Volume24
Issue number2
DOIs
StatePublished - Feb 2007
Externally publishedYes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Computer Vision and Pattern Recognition

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