TY - JOUR
T1 - Development and initial testing of TOGETHER-YA
T2 - an eHealth-delivered and group-based psychosocial intervention for young adult cancer survivors
AU - Oswald, Laura B.
AU - Lyleroehr, Madison
AU - Gudenkauf, Lisa M.
AU - Armstrong, Grace E.
AU - Tometich, Danielle B.
AU - Sanford, Stacy D.
AU - Loecher, Nele
AU - Geiss, Carley
AU - Rodriguez, Yvelise
AU - Scheel, Kelsey L.
AU - Nieves-Lopez, Amarilis
AU - Jim, Heather S.L.
AU - Gonzalez, Brian D.
AU - Antoni, Michael H.
AU - Penedo, Frank J.
AU - Reed, Damon
AU - Katsanis, Emmanuel
AU - Salsman, John M.
AU - Victorson, David
AU - Fox, Rina S.
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022/12
Y1 - 2022/12
N2 - Purpose: This study aimed to (1) develop TOGETHER-YA, an e-Health-delivered and group-based health-related quality of life (HRQOL) intervention for young adult (YA) cancer survivors aged 18–39 (Part 1), and (2) determine its initial feasibility and acceptability in a single-arm pilot trial (Part 2). Methods: TOGETHER-YA is a manualized, 10-week intervention for YA survivors that includes elements of relaxation training, cognitive-behavioral therapy, and health education. In Part 1, content was adapted from existing evidence-based interventions with feedback from YAs (N = 22) in four iterative focus groups. In Part 2, YA survivors (N = 11) participated in a single-arm pilot trial of TOGETHER-YA. Intervention groups were led by a trained facilitator over videoconference. Primary outcomes were feasibility (i.e., recruitment, session attendance, retention) and acceptability (i.e., participant satisfaction). Results: Focus groups reacted positively to TOGETHER-YA and provided actionable recommendations for enhancing its relevance and acceptability, which were implemented. In initial testing, all feasibility and acceptability benchmarks were met; 58% of eligible YAs were recruited, participants attended M = 6 intervention sessions (SD = 3), and 82% of participants were retained post-intervention. On average, participants “agreed” to “strongly agreed” with positive statements about the weekly sessions and the overall program. Conclusion: TOGETHER-YA was developed in collaboration with YA cancer survivors and found to be feasible and acceptable in initial testing. TOGETHER-YA is the first HRQOL intervention for a broad range of YA survivors that is eHealth-delivered for convenience and group-based for peer support. Future large-scale trials should test its efficacy for improving HRQOL. Trial registration: NCT05048316, September 17, 2021; NCT05054569, September 23, 2021.
AB - Purpose: This study aimed to (1) develop TOGETHER-YA, an e-Health-delivered and group-based health-related quality of life (HRQOL) intervention for young adult (YA) cancer survivors aged 18–39 (Part 1), and (2) determine its initial feasibility and acceptability in a single-arm pilot trial (Part 2). Methods: TOGETHER-YA is a manualized, 10-week intervention for YA survivors that includes elements of relaxation training, cognitive-behavioral therapy, and health education. In Part 1, content was adapted from existing evidence-based interventions with feedback from YAs (N = 22) in four iterative focus groups. In Part 2, YA survivors (N = 11) participated in a single-arm pilot trial of TOGETHER-YA. Intervention groups were led by a trained facilitator over videoconference. Primary outcomes were feasibility (i.e., recruitment, session attendance, retention) and acceptability (i.e., participant satisfaction). Results: Focus groups reacted positively to TOGETHER-YA and provided actionable recommendations for enhancing its relevance and acceptability, which were implemented. In initial testing, all feasibility and acceptability benchmarks were met; 58% of eligible YAs were recruited, participants attended M = 6 intervention sessions (SD = 3), and 82% of participants were retained post-intervention. On average, participants “agreed” to “strongly agreed” with positive statements about the weekly sessions and the overall program. Conclusion: TOGETHER-YA was developed in collaboration with YA cancer survivors and found to be feasible and acceptable in initial testing. TOGETHER-YA is the first HRQOL intervention for a broad range of YA survivors that is eHealth-delivered for convenience and group-based for peer support. Future large-scale trials should test its efficacy for improving HRQOL. Trial registration: NCT05048316, September 17, 2021; NCT05054569, September 23, 2021.
KW - Cancer survivors
KW - Clinical trials, non-randomized
KW - Psychosocial intervention
KW - Qualitative research
KW - Young adult
UR - http://www.scopus.com/inward/record.url?scp=85139853855&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85139853855&partnerID=8YFLogxK
U2 - 10.1007/s00520-022-07382-y
DO - 10.1007/s00520-022-07382-y
M3 - Article
C2 - 36229547
AN - SCOPUS:85139853855
SN - 0941-4355
VL - 30
SP - 10067
EP - 10076
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
IS - 12
ER -