TY - JOUR
T1 - Detection of Positive and Negative Ions from a Flowing Atmospheric Pressure Afterglow Using a Mattauch-Herzog Mass Spectrograph Equipped with a Faraday-Strip Array Detector
AU - Schilling, Gregory D.
AU - Shelley, Jacob T.
AU - Barnes, James H.
AU - Sperline, Roger P.
AU - Denton, M. Bonner
AU - Barinaga, Charles J.
AU - Koppenaal, David W.
AU - Hieftje, Gary M.
N1 - Funding Information:
The authors acknowledge support in part for this work by the U.S. Department of Energy, Office of Nonproliferation Research and Engineering. Pacific Northwest National Laboratory is operated by Battelle Memorial Institute for the Department of Energy under Contract DE-AC06-76RLO-1830. The authors also acknowledge support in part also by Prosolia, Inc. and by the Indiana METACyt Initiative of Indiana University, funded in part through a major grant from the Lilly Endowment, Inc.
PY - 2010/1
Y1 - 2010/1
N2 - An ambient desorption/ionization (ADI) source, known as the flowing atmospheric pressure afterglow (FAPA), has been coupled to a Mattauch-Herzog mass spectrograph (MHMS) equipped with a focal plane camera (FPC) array detector. The FAPA ionization source enables direct mass spectral analysis of solids, liquids, and gases through either positive or negative ionization modes. In either case, spectra are generally simple with dominant peaks being the molecular ions or protonated molecular ions. Use of the FAPA source with the MHMS allows the FPC detector to be characterized for the determination of molecular species, whereas previously only atomic mass spectrometry (MS) has been demonstrated. Furthermore, the FPC is shown to be sensitive to negative ions without the need to change any detector parameters. The analysis of solid, liquid, and gaseous samples through positive and negative ionization is demonstrated with detection limits (1-25 fmol/s, ∼0.3-10 pg of analyte per mL of helium) surpassing those obtained with the FAPA source coupled to a time-of-flight mass analyzer.
AB - An ambient desorption/ionization (ADI) source, known as the flowing atmospheric pressure afterglow (FAPA), has been coupled to a Mattauch-Herzog mass spectrograph (MHMS) equipped with a focal plane camera (FPC) array detector. The FAPA ionization source enables direct mass spectral analysis of solids, liquids, and gases through either positive or negative ionization modes. In either case, spectra are generally simple with dominant peaks being the molecular ions or protonated molecular ions. Use of the FAPA source with the MHMS allows the FPC detector to be characterized for the determination of molecular species, whereas previously only atomic mass spectrometry (MS) has been demonstrated. Furthermore, the FPC is shown to be sensitive to negative ions without the need to change any detector parameters. The analysis of solid, liquid, and gaseous samples through positive and negative ionization is demonstrated with detection limits (1-25 fmol/s, ∼0.3-10 pg of analyte per mL of helium) surpassing those obtained with the FAPA source coupled to a time-of-flight mass analyzer.
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U2 - 10.1016/j.jasms.2009.09.009
DO - 10.1016/j.jasms.2009.09.009
M3 - Article
C2 - 19889553
AN - SCOPUS:73449093154
SN - 1044-0305
VL - 21
SP - 97
EP - 103
JO - Journal of the American Society for Mass Spectrometry
JF - Journal of the American Society for Mass Spectrometry
IS - 1
ER -