Abstract
Rigid linkers of variable length were synthesized and used to connect two NDP-α-MSH ligands. The linkers were incorporated by solid-phase synthesis. Biological evaluations indicate that there is virtually no effect of these linkers on ligand binding to the human melanocortin 4 receptor.
Original language | English (US) |
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Pages (from-to) | 7589-7592 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 46 |
Issue number | 44 |
DOIs | |
State | Published - Oct 31 2005 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry