TY - JOUR
T1 - Design of peptide hormone and neurotransmitter analogues
AU - Hruby, Victor J.
PY - 1985
Y1 - 1985
N2 - Peptides are being found to be increasingly important as hormones and neurotransmitters, and much reasearch is directed towards elucidating the physiological roles of these natural products in pain, reproduction, maintenance of blood glucose levels etc. In this review, Victor Hruby describes some of the conformational approaches that have led to significant insights into the chemical and physical properties of these compounds and so to the rational design of analogues with new and specific properties.
AB - Peptides are being found to be increasingly important as hormones and neurotransmitters, and much reasearch is directed towards elucidating the physiological roles of these natural products in pain, reproduction, maintenance of blood glucose levels etc. In this review, Victor Hruby describes some of the conformational approaches that have led to significant insights into the chemical and physical properties of these compounds and so to the rational design of analogues with new and specific properties.
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U2 - 10.1016/0165-6147(85)90119-1
DO - 10.1016/0165-6147(85)90119-1
M3 - Article
AN - SCOPUS:0000576232
VL - 6
SP - 259
EP - 262
JO - Trends in Pharmacological Sciences
JF - Trends in Pharmacological Sciences
SN - 0165-6147
IS - C
ER -