Derivatized cyclodextrins as peptidomimetics: Influence on neurite growth

Alison M.P. Borrajo, Boris I. Gorin, Suzanne M. Dostaler, Richard J. Riopelle, Gregory R.J. Thatcher

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Per-6-bromo-6-deoxy-cyclodextrins may be functionalized to yield amine-derivatized cyclodextrin mimics of glycosaminoglycan sulfate binding domains of peptides, which inhibit neurite growth in vitro.

Original languageEnglish (US)
Pages (from-to)1185-1190
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume7
Issue number9
DOIs
StatePublished - May 6 1997
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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