Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

Karen L. Weihs; Samuel J. Simmens; Joan Mizrahi; Timothy M. Enright; Martha E. Hunt; Robert S. Siegel

doi:10.1016/j.jpsychores.2004.12.002

Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

Karen L. Weihs
, Samuel J. Simmens
, Joan Mizrahi
, Timothy M. Enright
, Martha E. Hunt
, Robert S. Siegel

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

Original language	English (US)
Pages (from-to)	299-306
Number of pages	8
Journal	Journal of Psychosomatic Research
Volume	59
Issue number	5
DOIs	https://doi.org/10.1016/j.jpsychores.2004.12.002
State	Published - Nov 2005
Externally published	Yes

Keywords

Breast cancer
Psychosocial factors
Social support
Survival

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

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10.1016/j.jpsychores.2004.12.002

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@article{6a66685105ff4f2abb41f46c3cdb4da4,

title = "Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients",

abstract = "Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.",

keywords = "Breast cancer, Psychosocial factors, Social support, Survival",

author = "Weihs, \{Karen L.\} and Simmens, \{Samuel J.\} and Joan Mizrahi and Enright, \{Timothy M.\} and Hunt, \{Martha E.\} and Siegel, \{Robert S.\}",

note = "Funding Information: This research was supported by ADAMHA Grant K20 MH00906 to Karen Weihs, MD. It was presented at the American Psychosomatic Society, 59th Annual Scientific Meeting, March 6–11, 2001; Monterey, CA. ",

year = "2005",

month = nov,

doi = "10.1016/j.jpsychores.2004.12.002",

language = "English (US)",

volume = "59",

pages = "299--306",

journal = "Journal of Psychosomatic Research",

issn = "0022-3999",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

AU - Weihs, Karen L.

AU - Simmens, Samuel J.

AU - Mizrahi, Joan

AU - Enright, Timothy M.

AU - Hunt, Martha E.

AU - Siegel, Robert S.

N1 - Funding Information: This research was supported by ADAMHA Grant K20 MH00906 to Karen Weihs, MD. It was presented at the American Psychosomatic Society, 59th Annual Scientific Meeting, March 6–11, 2001; Monterey, CA.

PY - 2005/11

Y1 - 2005/11

N2 - Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

AB - Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

KW - Breast cancer

KW - Psychosocial factors

KW - Social support

KW - Survival

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Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

Abstract

Keywords

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