Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

Karen L. Weihs; Samuel J. Simmens; Joan Mizrahi; Timothy M. Enright; Martha E. Hunt; Robert S. Siegel

doi:10.1016/j.jpsychores.2004.12.002

Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

Karen L. Weihs, Samuel J. Simmens, Joan Mizrahi, Timothy M. Enright, Martha E. Hunt, Robert S. Siegel

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

Original language	English (US)
Pages (from-to)	299-306
Number of pages	8
Journal	Journal of Psychosomatic Research
Volume	59
Issue number	5
DOIs	https://doi.org/10.1016/j.jpsychores.2004.12.002
State	Published - Nov 2005

Keywords

Breast cancer
Psychosocial factors
Social support
Survival

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

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10.1016/j.jpsychores.2004.12.002

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title = "Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients",

abstract = "Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.",

keywords = "Breast cancer, Psychosocial factors, Social support, Survival",

author = "Weihs, {Karen L.} and Simmens, {Samuel J.} and Joan Mizrahi and Enright, {Timothy M.} and Hunt, {Martha E.} and Siegel, {Robert S.}",

note = "Funding Information: This research was supported by ADAMHA Grant K20 MH00906 to Karen Weihs, MD. It was presented at the American Psychosomatic Society, 59th Annual Scientific Meeting, March 6–11, 2001; Monterey, CA. ",

year = "2005",

month = nov,

doi = "10.1016/j.jpsychores.2004.12.002",

language = "English (US)",

volume = "59",

pages = "299--306",

journal = "Journal of Psychosomatic Research",

issn = "0022-3999",

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TY - JOUR

T1 - Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

AU - Weihs, Karen L.

AU - Simmens, Samuel J.

AU - Mizrahi, Joan

AU - Enright, Timothy M.

AU - Hunt, Martha E.

AU - Siegel, Robert S.

N1 - Funding Information: This research was supported by ADAMHA Grant K20 MH00906 to Karen Weihs, MD. It was presented at the American Psychosomatic Society, 59th Annual Scientific Meeting, March 6–11, 2001; Monterey, CA.

PY - 2005/11

Y1 - 2005/11

N2 - Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

AB - Objective: The effect of support, from dependable non-household relationships, on breast cancer progression was studied using a prospective, longitudinal design. Methods: Dependable social support was assessed in women with invasive breast carcinoma Stages II and III within 18 months after diagnosis. Disease outcome was monitored for 8 to 9 years. Cox regression analyses, including the Nottingham Prognostic Index (NPI) score of disease severity, tested the association between the number of dependable support persons and time to death. Results: Ninety participants listed between 1 and 16 dependable nonhousehold support persons (mean=6, S.D.=4). There were 21 recurrences and 16 deaths from breast cancer at the end of the study. The number of dependable supports predicted decreased mortality [RR=0.41 (0.21-0.80), P=.01] after controlling for NPI. NPI predicted increased mortality [RR=1.6 (1.0, 2.4), P=.05]. Conclusions: For patients with Stages II and III breast cancer, the number of dependable, nonhousehold relationships predicts decreased mortality, after accounting for disease severity.

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KW - Psychosocial factors

KW - Social support

KW - Survival

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Dependable social relationships predict overall survival in Stages II and III breast carcinoma patients

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