Abstract
While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4914-4916 |
| Number of pages | 3 |
| Journal | Journal of virology |
| Volume | 78 |
| Issue number | 9 |
| DOIs | |
| State | Published - May 2004 |
| Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology