das Schicksal Kardialer Zelltransplantate: IIn-vivo-beobachtung des Zell̈uberlebens mit Optischer Biolumineszenz - Ernst-derra-preis der DGTHG 2008

In vivo optical imaging of cardiac cell grafting is a reliable technique to follow the early survival kinetics of cardiac cell grafts. The superficial position of the heart in this heterotopic transplant model contributes to superior signal intensity and provides reliable cell detection. This non-invasive imaging technique in conjunction with the established surgical heterotopic heart transplant model will allow investigators to further study cardiac cell graft survival with modulation by a variety of therapeutic agents. Collagen based matrices improve early H9c2-cardiomyoblast survival after cell transfer into infarcted myocardium.