Dad's not having much pain: Fatal forty DDI: Methadone, ciprofloxacin, CYP3A4

Rani Chovatiya; Mehmet S. Ozcan; Randal O. Dull

doi:10.1007/978-1-4614-7495-1_51

Dad's not having much pain: Fatal forty DDI: Methadone, ciprofloxacin, CYP3A4

Rani Chovatiya, Mehmet S. Ozcan, Randal O. Dull

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses a pharmacokinetic interaction between methadone and ciprofloxacin resulting in increased sedative and analgesic effects of methadone. Methadone is a cytochrome P450 3A4 substrate and ciprofloxacin is a 3A4 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	249-251
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_51
State	Published - Sep 15 2015
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_51

Cite this

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abstract = "This case discusses a pharmacokinetic interaction between methadone and ciprofloxacin resulting in increased sedative and analgesic effects of methadone. Methadone is a cytochrome P450 3A4 substrate and ciprofloxacin is a 3A4 inhibitor.",

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Dad's not having much pain: Fatal forty DDI: Methadone, ciprofloxacin, CYP3A4

Abstract

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