Cyathocaline, an azafluorenone alkaloid from cyathocalyx zeylanica

E. M. Kithsiri Wijeratne; Leslie B. De Silva; Tohru Kikuchi; Yasuhiro Tezuka; A. A. Leslie Gunatilaka; David G.I. Kingston

doi:10.1021/np50117a020

Cyathocaline, an azafluorenone alkaloid from cyathocalyx zeylanica

E. M. Kithsiri Wijeratne, Leslie B. De Silva, Tohru Kikuchi, Yasuhiro Tezuka, A. A. Leslie Gunatilaka, David G.I. Kingston

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Bioactivity-guided fractionation of a MeOH extract of the stem bark of Cyathocalyx zeylanica afforded a moderately bioactive new azafluorenone alkaloid, cyathocaline, the structure of which was established as 5,7-dihydroxy-6-methoxy-1-methyl-4-azafluoren-9-one [1] with the aid of spectroscopic data.

Original language	English (US)
Pages (from-to)	459-462
Number of pages	4
Journal	Journal Of Natural Products
Volume	58
Issue number	3
DOIs	https://doi.org/10.1021/np50117a020
State	Published - Mar 1995
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "Cyathocaline, an azafluorenone alkaloid from cyathocalyx zeylanica",

abstract = "Bioactivity-guided fractionation of a MeOH extract of the stem bark of Cyathocalyx zeylanica afforded a moderately bioactive new azafluorenone alkaloid, cyathocaline, the structure of which was established as 5,7-dihydroxy-6-methoxy-1-methyl-4-azafluoren-9-one [1] with the aid of spectroscopic data.",

author = "{Kithsiri Wijeratne}, {E. M.} and {De Silva}, {Leslie B.} and Tohru Kikuchi and Yasuhiro Tezuka and {Leslie Gunatilaka}, {A. A.} and Kingston, {David G.I.}",

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AU - Kithsiri Wijeratne, E. M.

AU - De Silva, Leslie B.

AU - Kikuchi, Tohru

AU - Tezuka, Yasuhiro

AU - Leslie Gunatilaka, A. A.

AU - Kingston, David G.I.

PY - 1995/3

Y1 - 1995/3

N2 - Bioactivity-guided fractionation of a MeOH extract of the stem bark of Cyathocalyx zeylanica afforded a moderately bioactive new azafluorenone alkaloid, cyathocaline, the structure of which was established as 5,7-dihydroxy-6-methoxy-1-methyl-4-azafluoren-9-one [1] with the aid of spectroscopic data.

AB - Bioactivity-guided fractionation of a MeOH extract of the stem bark of Cyathocalyx zeylanica afforded a moderately bioactive new azafluorenone alkaloid, cyathocaline, the structure of which was established as 5,7-dihydroxy-6-methoxy-1-methyl-4-azafluoren-9-one [1] with the aid of spectroscopic data.

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Cyathocaline, an azafluorenone alkaloid from cyathocalyx zeylanica

Abstract

ASJC Scopus subject areas

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