Cucurbitacins of Colocynthis vulgaris

Chandra B. Gamlath, A. A.Leslie Gunatilaka, Khisal A. Alvi, Atta-ur-Rahman, Sinnathamby Balasubramaniam

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24S)-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic significance of the co-occurrence of cucurbitacins I, J and T in C. vulgaris is discussed.

Original languageEnglish (US)
Pages (from-to)3225-3229
Number of pages5
Issue number10
StatePublished - 1988


  • Citrullus colocynthis, Cucurbitaceae
  • Colocynthis vulgaris
  • biosynthesis.
  • cucurbitacin I
  • cucurbitacin J
  • cucurbitacin T
  • structure elucidation

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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