Cucurbitacins of Colocynthis vulgaris

Chandra B. Gamlath; A. A.Leslie Gunatilaka; Khisal A. Alvi; Atta-ur-Rahman; Sinnathamby Balasubramaniam

doi:10.1016/0031-9422(88)80031-1

Cucurbitacins of Colocynthis vulgaris

Chandra B. Gamlath, A. A.Leslie Gunatilaka, Khisal A. Alvi, Atta-ur-Rahman, Sinnathamby Balasubramaniam

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24S)-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic significance of the co-occurrence of cucurbitacins I, J and T in C. vulgaris is discussed.

Original language	English (US)
Pages (from-to)	3225-3229
Number of pages	5
Journal	Phytochemistry
Volume	27
Issue number	10
DOIs	https://doi.org/10.1016/0031-9422(88)80031-1
State	Published - 1988

Keywords

Citrullus colocynthis, Cucurbitaceae
Colocynthis vulgaris
biosynthesis.
cucurbitacin I
cucurbitacin J
cucurbitacin T
structure elucidation

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/0031-9422(88)80031-1

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title = "Cucurbitacins of Colocynthis vulgaris",

abstract = "The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24S)-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic significance of the co-occurrence of cucurbitacins I, J and T in C. vulgaris is discussed.",

keywords = "Citrullus colocynthis, Cucurbitaceae, Colocynthis vulgaris, biosynthesis., cucurbitacin I, cucurbitacin J, cucurbitacin T, structure elucidation",

author = "Gamlath, {Chandra B.} and Gunatilaka, {A. A.Leslie} and Alvi, {Khisal A.} and Atta-ur-Rahman and Sinnathamby Balasubramaniam",

year = "1988",

doi = "10.1016/0031-9422(88)80031-1",

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volume = "27",

pages = "3225--3229",

journal = "Phytochemistry",

issn = "0031-9422",

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T1 - Cucurbitacins of Colocynthis vulgaris

AU - Gamlath, Chandra B.

AU - Gunatilaka, A. A.Leslie

AU - Alvi, Khisal A.

AU - Atta-ur-Rahman,

AU - Balasubramaniam, Sinnathamby

PY - 1988

Y1 - 1988

N2 - The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24S)-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic significance of the co-occurrence of cucurbitacins I, J and T in C. vulgaris is discussed.

AB - The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24S)-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic significance of the co-occurrence of cucurbitacins I, J and T in C. vulgaris is discussed.

KW - Citrullus colocynthis, Cucurbitaceae

KW - Colocynthis vulgaris

KW - biosynthesis.

KW - cucurbitacin I

KW - cucurbitacin J

KW - cucurbitacin T

KW - structure elucidation

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EP - 3229

JO - Phytochemistry

JF - Phytochemistry

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IS - 10

ER -

Cucurbitacins of Colocynthis vulgaris

Abstract

Keywords

ASJC Scopus subject areas

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