CT of the pancreas with a fat-density oral contrast regimen

V. Raptopoulos, A. Davidoff, A. Karellas, M. A. Davis, B. L. Coolbaugh, E. H. Smith

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8 Scopus citations


Visualization of the head of the pancreas by CT was prospectively evaluated in two groups of 100 patients who did not have pancreatic disease. Patients were given either a fat-density oral contrast material (12.5% corn-oil emulsion and metoclopramide) or a conventional high-density oral contrast material (barium suspension or iodinated solution). There was no statistically significant difference in the subjects' tolerance to the two regimens. There was, however, a significant improvement in ability to distinguish the head of the pancreas from the duodenal C-loop when the fat-density contrast material was given. When pancreaticoduodenal discrimination was graded, patients given corn-oil emulsion and metoclopramide received an average score of 0.94, whereas those given the high-density agent received an average score of 0.74, with 1.00 being the highest possible score (p < .005). These data suggest that for routine CT evaluation of the head of the pancreas, a combination of corn-oil emulsion and metoclopramide may be superior to the conventional high-density oral contrast agents given without metoclopramide.

Original languageEnglish (US)
Pages (from-to)1303-1306
Number of pages4
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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