Cryosurgery of cervical intraepithelial neoplasia

Kenneth D. Hatch, Hugh M. Shingleton, J. Max Austin, Seng Jaw Soong, Dorothy H. Bradley

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Nine hundred sixty-eight patients with cervical intraepithelial neoplasia (CIN) were evaluated with colposcopy and treated with cryosurgery; 722 had a pretreatment diagnosis of CIN I or II and 246 had CIN III. Of those patients available for 2 follow-up smears, histologically proved persistence of CIN was found in 10% of patients with CIN I and II and 20% of patients with CIN III. Recurrent disease was detected in 3.2 and 3.8%, respectively. No patient had a recurrence after 5 negative Papanicolaou smears. One patient had invasive carcinoma 30 months after treatment. Failure of patients to return for follow-up was a significant problem. When the present results were compared to those published in the literature, cryosurgery was found to be less effective than conization in treating CIN III.

Original languageEnglish (US)
Pages (from-to)692-698
Number of pages7
JournalObstetrics and gynecology
Issue number6
StatePublished - Jun 1981

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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