Covalently cross-linked Watson-Crick base pair models. Part 2

Yao Ling Qiu; Hong Yu Li; George Topalov; Yoshito Kishi

doi:10.1016/S0040-4039(00)01572-0

Covalently cross-linked Watson-Crick base pair models. Part 2

Yao Ling Qiu, Hong Yu Li, George Topalov, Yoshito Kishi

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A concise and practical route has been developed for a synthesis of the CH₂-bridged base pairs represented by the type-II structure. The structural studies suggest the possibility that these base pairs mimic the molecular architecture of Watson-Crick hydrogen-bonded base pairs.

Original language	English (US)
Pages (from-to)	9425-9429
Number of pages	5
Journal	Tetrahedron Letters
Volume	41
Issue number	49
DOIs	https://doi.org/10.1016/S0040-4039(00)01572-0
State	Published - Dec 2 2000

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)01572-0

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title = "Covalently cross-linked Watson-Crick base pair models. Part 2",

abstract = "A concise and practical route has been developed for a synthesis of the CH2-bridged base pairs represented by the type-II structure. The structural studies suggest the possibility that these base pairs mimic the molecular architecture of Watson-Crick hydrogen-bonded base pairs.",

author = "Qiu, {Yao Ling} and Li, {Hong Yu} and George Topalov and Yoshito Kishi",

note = "Funding Information: Financial support from the National Institutes of Health (NS 12108) is gratefully acknowledged. ",

year = "2000",

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doi = "10.1016/S0040-4039(00)01572-0",

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T1 - Covalently cross-linked Watson-Crick base pair models. Part 2

AU - Qiu, Yao Ling

AU - Li, Hong Yu

AU - Topalov, George

AU - Kishi, Yoshito

N1 - Funding Information: Financial support from the National Institutes of Health (NS 12108) is gratefully acknowledged.

PY - 2000/12/2

Y1 - 2000/12/2

N2 - A concise and practical route has been developed for a synthesis of the CH2-bridged base pairs represented by the type-II structure. The structural studies suggest the possibility that these base pairs mimic the molecular architecture of Watson-Crick hydrogen-bonded base pairs.

AB - A concise and practical route has been developed for a synthesis of the CH2-bridged base pairs represented by the type-II structure. The structural studies suggest the possibility that these base pairs mimic the molecular architecture of Watson-Crick hydrogen-bonded base pairs.

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U2 - 10.1016/S0040-4039(00)01572-0

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M3 - Article

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EP - 9429

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Covalently cross-linked Watson-Crick base pair models. Part 2

Abstract

ASJC Scopus subject areas

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