Cosolvency. I. Some Non-Hydrogen Bonding Solutes with Non-Hydrogen Bonding Solvents

Monica Chawla; Rodolfo Pinal; Kenneth R. Morris; SAmuel H. Yalkowsky

doi:10.1080/02772248709357235

Cosolvency. I. Some Non-Hydrogen Bonding Solutes with Non-Hydrogen Bonding Solvents

Monica Chawla, Rodolfo Pinal, Kenneth R. Morris, SAmuel H. Yalkowsky

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The solubility data for a series of non-hydrogen bonding, monosubstituted benzenes in binary mixtures of water and non-hydrogen bonding cosolvents is presented. Good correlation between log solubility and fraction cosolvent is obtained, therefore the estimation of solubility in mixed solvents by a log-linear relationship can be attained. Slight positive or negative deviations from predicted solubility values are seen at high volume fractions of cosolvents. These deviations are attributed to the cosolvent-water interactions.

Original language	English (US)
Pages (from-to)	237-247
Number of pages	11
Journal	Toxicological & Environmental Chemistry
Volume	15
Issue number	4
DOIs	https://doi.org/10.1080/02772248709357235
State	Published - Jul 1 1987

Keywords

Solubility data
cosolvency
non-hydrogen bonding solutes
substituted benzenes

ASJC Scopus subject areas

Environmental Chemistry
Pollution
Health, Toxicology and Mutagenesis

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10.1080/02772248709357235

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abstract = "The solubility data for a series of non-hydrogen bonding, monosubstituted benzenes in binary mixtures of water and non-hydrogen bonding cosolvents is presented. Good correlation between log solubility and fraction cosolvent is obtained, therefore the estimation of solubility in mixed solvents by a log-linear relationship can be attained. Slight positive or negative deviations from predicted solubility values are seen at high volume fractions of cosolvents. These deviations are attributed to the cosolvent-water interactions.",

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author = "Monica Chawla and Rodolfo Pinal and Morris, {Kenneth R.} and Yalkowsky, {SAmuel H.}",

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AU - Chawla, Monica

AU - Pinal, Rodolfo

AU - Morris, Kenneth R.

AU - Yalkowsky, SAmuel H.

PY - 1987/7/1

Y1 - 1987/7/1

N2 - The solubility data for a series of non-hydrogen bonding, monosubstituted benzenes in binary mixtures of water and non-hydrogen bonding cosolvents is presented. Good correlation between log solubility and fraction cosolvent is obtained, therefore the estimation of solubility in mixed solvents by a log-linear relationship can be attained. Slight positive or negative deviations from predicted solubility values are seen at high volume fractions of cosolvents. These deviations are attributed to the cosolvent-water interactions.

AB - The solubility data for a series of non-hydrogen bonding, monosubstituted benzenes in binary mixtures of water and non-hydrogen bonding cosolvents is presented. Good correlation between log solubility and fraction cosolvent is obtained, therefore the estimation of solubility in mixed solvents by a log-linear relationship can be attained. Slight positive or negative deviations from predicted solubility values are seen at high volume fractions of cosolvents. These deviations are attributed to the cosolvent-water interactions.

KW - Solubility data

KW - cosolvency

KW - non-hydrogen bonding solutes

KW - substituted benzenes

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JF - Toxicological & Environmental Chemistry

IS - 4

ER -

Cosolvency. I. Some Non-Hydrogen Bonding Solutes with Non-Hydrogen Bonding Solvents

Abstract

Keywords

ASJC Scopus subject areas

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