Correspondence on Lovell et al.: Identification of chicken genes previously assumed to be evolutionarily lost

Susanne Bornelöv; Eyal Seroussi; Sara Yosefi; Ken Pendavis; Shane C. Burgess; Manfred Grabherr; Miriam Friedman-Einat; Leif Andersson

doi:10.1186/s13059-017-1231-1

Correspondence on Lovell et al. Identification of chicken genes previously assumed to be evolutionarily lost

Susanne Bornelöv, Eyal Seroussi, Sara Yosefi, Ken Pendavis, Shane C. Burgess, Manfred Grabherr, Miriam Friedman-Einat, Leif Andersson

Research output: Contribution to journal › Letter › peer-review

35 Scopus citations

Abstract

Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

Original language	English (US)
Article number	112
Journal	Genome biology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1186/s13059-017-1231-1
State	Published - Jun 14 2017

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/s13059-017-1231-1

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title = "Correspondence on Lovell et al.: Identification of chicken genes previously assumed to be evolutionarily lost",

abstract = "Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.",

author = "Susanne Bornel{\"o}v and Eyal Seroussi and Sara Yosefi and Ken Pendavis and Burgess, {Shane C.} and Manfred Grabherr and Miriam Friedman-Einat and Leif Andersson",

note = "Funding Information: We thank Mr Mark Ruzal for growing the chickens. The study was supported by the ERC project BATESON (awarded to LA), Israel Academy of Sciences 876/14, and by the Chief Scientist of the Israeli Ministry of Agriculture 0469/14 (awarded to MFE and ES). Publisher Copyright: {\textcopyright} 2017 The Author(s).",

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AU - Bornelöv, Susanne

AU - Seroussi, Eyal

AU - Yosefi, Sara

AU - Pendavis, Ken

AU - Burgess, Shane C.

AU - Grabherr, Manfred

AU - Friedman-Einat, Miriam

AU - Andersson, Leif

N1 - Funding Information: We thank Mr Mark Ruzal for growing the chickens. The study was supported by the ERC project BATESON (awarded to LA), Israel Academy of Sciences 876/14, and by the Chief Scientist of the Israeli Ministry of Agriculture 0469/14 (awarded to MFE and ES). Publisher Copyright: © 2017 The Author(s).

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Y1 - 2017/6/14

N2 - Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

AB - Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

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Correspondence on Lovell et al. Identification of chicken genes previously assumed to be evolutionarily lost

Abstract

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