Correlation of Octanol/Water Solubility Ratios and Partition Coefficients

Sirirat Pinsuwan, An Li, Samuel H. Yalkowsky

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


The octanol/water solubility ratio (So/Sw) was found to be highly correlated with the octanol/water partition coefficient (Kow) of 82 pharmaceutically and environmentally relevant compounds. The solubility ratio gives comparable estimates to that of the group contribution (log P(calcd)) method for estimating the partition coefficient of the compounds used in this study.

Original languageEnglish (US)
Pages (from-to)623-626
Number of pages4
JournalJournal of Chemical and Engineering Data
Issue number3
StatePublished - May 1 1995

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering


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