Coronary perfusion pressure during cardiopulmonary resuscitation

Arthur B. Sanders, Martin Ogle, Gordon A. Ewy

Research output: Contribution to journalArticlepeer-review

82 Scopus citations


Currently, there is no way to measure the effectiveness of cardiopulmonary resuscitation in humans. The literature suggests that minimum aortic diastolic and estimated coronary perfusion pressures during cardiopulmonary resuscitation (CPR) in the animal model correlate with higher resuscitation rates. Six patients were studied during CPR to determine the arterial diastolic and estimated coronary perfusion pressures (arterial minus right atrial diastolic pressures). Mean arterial pressures were 27 11 mm Hg, central venous pressures were 32 10 mm Hg, and the mean estimated coronary perfusion pressure was only 1 mm Hg. None of the six patients survived. This study demonstrates that the techniques of measuring hemodynamic values during CPR is practical. Poor estimated coronary perfusion pressures were obtained from the six patients studied. This study should be extended to include a large number of patients to determine whether these hemodynamic parameters can be used as prognostic indicators of successful resuscitation in humans.

Original languageEnglish (US)
Pages (from-to)11-14
Number of pages4
JournalAmerican Journal of Emergency Medicine
Issue number1
StatePublished - Jan 1985


  • Cardiopulmonary resuscitation
  • coronary perfusion

ASJC Scopus subject areas

  • Emergency Medicine


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