Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin

  • Guojun Wang
  • , Pallab Pahari
  • , Madan K. Kharel
  • , Jing Chen
  • , Haining Zhu
  • , Steven G. Vanlanen
  • , Jürgen Rohr

Research output: Contribution to journalArticlepeer-review

25 Scopus citations
Original languageEnglish (US)
Pages (from-to)10638-10642
Number of pages5
JournalAngewandte Chemie - International Edition
Volume51
Issue number42
DOIs
StatePublished - Oct 15 2012
Externally publishedYes

Keywords

  • 4-ketoreductase
  • bifunctional enzymes
  • c-methyltransferase
  • glycosyltransferase
  • mithramycin

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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