Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation

Nathan W. Polaske; Michael L. Szalai; Charles S. Shanahan; Dominic V. McGrath

doi:10.1021/ol102081q

Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation

Nathan W. Polaske, Michael L. Szalai, Charles S. Shanahan, Dominic V. McGrath

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.

Original language	English (US)
Pages (from-to)	4944-4947
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	21
DOIs	https://doi.org/10.1021/ol102081q
State	Published - Nov 5 2010

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol102081q

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title = "Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation",

abstract = "The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.",

author = "Polaske, {Nathan W.} and Szalai, {Michael L.} and Shanahan, {Charles S.} and McGrath, {Dominic V.}",

year = "2010",

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T1 - Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation

AU - Polaske, Nathan W.

AU - Szalai, Michael L.

AU - Shanahan, Charles S.

AU - McGrath, Dominic V.

PY - 2010/11/5

Y1 - 2010/11/5

N2 - The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.

AB - The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.

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JO - Organic Letters

JF - Organic Letters

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ER -

Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation

Abstract

ASJC Scopus subject areas

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