Control of tetrazine bioorthogonal reactivity by naphthotube and phenyltetrazine host-guest pairs

Kaiyan Lou, Wanjin Xing, Xiang Meng, Mengyang Chang, Wei Wang

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations

Abstract

In this issue of Chem, high-affinity and high-specificity naphthotube and phenyltetrazine host-guest pairs are designed to control tetrazine reactivity in bioorthogonal chemistry. The power of the system has been demonstrated in precise labeling and functionalization of biological targets in chemical and biological systems, including in animal models.

Original languageEnglish (US)
Pages (from-to)2727-2730
Number of pages4
JournalChem
Volume9
Issue number10
DOIs
StatePublished - Oct 12 2023

Keywords

  • SDG3: Good health and well-being

ASJC Scopus subject areas

  • General Chemistry
  • Biochemistry
  • Environmental Chemistry
  • General Chemical Engineering
  • Biochemistry, medical
  • Materials Chemistry

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